Introduction:
Pre-clinical toxicology is a branch of toxicology which focuses on the evaluation of toxicity of new drugs, chemicals, or substances before they are tested in human clinical trials. This process ensures the safety of new products that may eventually be used by humans.
It includes animal testing to detect negative effects, to determine dose-response and estimating risks for human trials.
Importance of pre-clinical trials
- Preclinical trials evaluate the safety and effectiveness of new drugs before human testing.
- To determine the drug dosage, formulations, and negative effects.
- These studies provide insights for potential benefits and risks.
- It is important to check safety trials on animals before human trials.
- Successful preclinical testing is a critical milestone on the path to new medical treatments.
Pre-Clinical safety evaluation at AAL BIO sciences
We at AAL Bio sciences provides Pre-Clinical toxicities safety evaluation as per ISO10993 and OECD including genotoxicity, carcinogenicity, reproductive toxicity, tests for interactions with blood, in vitro cytotoxicity, local effects after implantation, skin irritation and skin sensitization, systemic toxicity, immunotoxicology testing of medical devices.
We also perform leachability, and chemical characterization of materials of medical devices as per ISO 10993-17 and ISO 10993- 18.